Allergy Statistics
Allergic rhinitis affects up to 30 percentage of the population worldwide.1 In the United States, approximately 7.5 percentage or 17.6 million adults were diagnosed with hay fever in the past 12 months.2 Likewise one in 12 people ( about 25 million, or 8 percentage of the U.S. population ) has asthma—that ’ s up from one in 14 people only a few years earlier.3 relatively, one in 10 children have asthma.4 Allergic disease, including asthma, is the fifth leading chronic disease in the U.S. in people of all ages. It is the third base most common chronic disease in children under 18 years old.5
Current Medical Treatment
presently there are two types of aesculapian treatment for allergies : medicine and immunotherapy. With regard to medications, the American College of Allergy, Asthma & Immunology says : “ Decongestants and antihistamines are the most common allergy medications. They help to reduce a stodgy nose, fluid nose, sneezing and itching. other medications work by preventing the release of the chemicals that cause allergic reactions. Corticosteroids are effective in treating excitement in your nose. ” 6 The drawback is that allergy medications besides have a meaning number of side effects. For model, WebMD indicates that some of the main side effects associated with antihistamines include dry mouth, sleepiness, dizziness, nausea and vomit, fidget or moodiness ( in some children ), trouble urinating or not being able to urinate, blurred sight and confusion. According to the American College of Allergy, Asthma & Immunology, “ Immunotherapy involves giving gradually increasing doses of the message, or allergen, to which the person is allergic. The incremental increases of the allergen cause the immune system to become less sensible to the meaning, credibly by causing product of a ‘ block ’ antibody, which reduces the symptoms of allergy when the substances is encountered in the future. Immunotherapy besides reduces the inflammation that characterizes rhinitis and asthma. ” But there are besides drawbacks to immunotherapy. This discussion is delivered via weekly injections ( a veto for some people ) or in oral kind, and is expensive. medical insurance may pay for the injections, but rarely pays for oral treatment. furthermore, it can take quite a long clock to get relief from allergic symptoms with immunotherapy—typically a year or more.
The Story of Quail Eggs
nowadays let ’ s shift gears and take a look at allergy discussion using AllerGuard Express. It all started in the early on 1970s when a french general practitioner noticed that farmers who raised quails presented fewer allergy symptoms than the general population in the same area. One quail farmer saw the gradual disappearance of existing asthma and changeless, allergy-related shortness of breath in his spouse and then that of his employees with the pulmonary tuberculosis of quail eggs. Another flinch farmer who experimented successfully with this treatment on his own family and friends confirmed this observation. The doctor then gave raw quail eggs to his allergy patients, including both adults and children, and observed a decrease in their symptoms.7 Subsequently investigations in respective human clinical trials were carried out by a larger group of physicians under the guidance of a highly respected french allergist, doctor Dr. G. Bruttmann. In these studies, subjects suffering from outdoor and indoor allergens were given AllerGuard Express tablets or placebo. In addition, each of the studies included a good size population and was double-blinded. The results of these studies indicated that consumption of AllerGuard Express led to relief of subjects ’ symptoms with beneficial tolerability of the distribute product. Following is a review of those studies .
Allerguard Express In the Treatment of Dust Mite-induced Allergic Asthma in Children
In a multi-center study,8 a group of 180 children with scatter mite-induced allergic asthma were treated with one pill casual of 21 mg AllerGuard Express or a placebo. The study took home over a 22-month time period. The results showed that AllerGuard Express was importantly better than placebo. In fact, there was a 77.7 percentage ( p < 0.001 ) reduction in the total of attacks at the goal of treatment, an improvement in respiratory function, and a 58.6 percentage reduction in the consumption of rescue medications by the AllerGuard Express group .
AllerGuard Express In the Treatment of Allergic Rhinitis
In a multi-center study,9 a group of 160 adults with pollen-induced allergic rhinitis were treated with one pill daily of 21 mg AllerGuard Express or a placebo. The report took place over an eight-month period. The results showed a statistically significant decrease in the intensity of allergic rhinitis in the treatment group compared to the placebo group ( p < 0.0001 ), with an improvement in all the symptoms considered. furthermore, there was a significant improvement in the condition of the rhinal mucous membrane compared to the placebo group ( phosphorus < 0.0001 ), and a meaning reduction in consumption of the rescue medication ( p < 0.0001 ). furthermore, these results were obtained at the acme of the pollen season. By the third calendar month, 70 percentage of the treat patients no long experienced any unpleasant symptoms. Another eight-month, multi-center study10 examined the effect of AllerGuard Express ( 21 mg/day ) or placebo in 180 adult patients with pollen-induced allergic rhinitis. As with the anterior study, results showed a statistically significant reduction in the intensity of allergic rhinitis in the flinch egg group compared to the placebo group ( p < 0.0001 ), improvement in all the symptoms and a meaning improvement in the stipulate of the nasal mucous membrane compared to the placebo group ( p < 0.0001 ). Likewise, a meaning reduction in consumption of the rescue medication ( p < 0.0001 ) was besides seen, and these results took position at the peak of the pollen season and were already meaning 45 days after the begin of treatment. By the third gear month, 80 percentage of the cover patients treated no longer experienced any symptoms or unpleasant symptoms. An extra eight-month, multi-center study11 examined the effect of AllerGuard Express ( 21 mg/day ) or placebo in 95 patients, 48 of whom were adults and 47 of whom where children, all with pollen-induced allergic rhinitis. As with the prior two studies, results showed a statistically significant decrease in the intensity of allergic rhinitis in the AllerGuard Express group compared to the placebo group ( p < 0.0001 ), with an improvement in all the symptoms and a significant improvement in the condition of the nasal mucous membrane compared to the placebo group ( phosphorus < 0.0001 ). once again, there was a significant reduction in consumption of the rescue medicine ( p < 0.0001 ), and once again these results were obtained at the point of the pollen season. The doctor assessed the overall efficacy as good or very good in 68.7 percentage of the patients treated with flinch testis powder ( p < 0.05 ). Unlike in seasonal rhinitis, the symptoms of perennial allergic rhinitis will normally be introduce throughout the entire class. Consequently, a 10-month, multi-center report examined the consequence of AllerGuard Express ( 21 mg/day ) or placebo in 124 pornographic patients with perennial allergic rhinitis. In this study, both the doctor of the church and the patient assessed the results. The doctor ’ s/patient ’ s judgment showed that the effect of discussion was significantly greater with AllerGuard Express ( 63.4 percent/65.7 percentage ) compared to the placebo group ( 27.3 percent/25 percentage ) ( phosphorus < 0.003 ), and that efficacy was seen after 28 days of discussion in terms of both adenoidal congestion and conjunctivitis/runny nose, sneezing and nasal congestion. altogether, there were 739 allergic patients in these five studies. In each discipline there was a significant improvement in allergy symptoms among those patients using AllerGuard Express over those using the placebo. Combining the results of all five studies 72 percentage of quail egg users experienced meaning remedy from allergy symptoms, while only 20 percentage of those in the placebo group experienced similar respite. It should be noted that in most of these studies, patients started supplementation about one month prior to expected allergic attacks. furthermore, progressive results were seen over a period of months with continue use. Nevertheless, significantly quicker relieve from allergy symptoms were seen with AllerGuard Express in the most holocene study .
Relief With AllerGuard Express in 15 Minutes
Most recently, a randomized, double-blind, two-arm crossing over, placebo-controlled, clinical trial12 was conducted in 43 adults. The participants were exposed to a concoction of the most prevailing outdoor and indoor allergens including grass and tree pollen, dust mites, arsenic well as computerized tomography and pawl dander. They then immediately took two tablets ( 42 magnesium of AllerGuard Express ) or placebo, both in the phase of chewable tablets, and were evaluated over a two-hour period. The results were that participants who AllerGuard Express were able to breathe significantly better through their nozzle ( 18 percentage improvement ; p≤0.05 vs. placebo ) starting american samoa soon as 15 minutes after allergen exposure and consumption of the tablets, and besides reported improvements in how they felt ranging from 25-44 percentage for airless nose, fluid nose, antsy nozzle, watery eyes and itchy eyes during the same 15 moment time period. Over the stallion two-hour post-challenge period, participants who took the AllerGuard Express reported they felt importantly better with attentiveness to stuffy intrude, fluid scent, itchy nose, watery eyes, and antsy eyes compared to how they felt after taking the placebo, and all without any adverse events .
How Does it Work?
Allergic rhinitis symptoms chiefly result from an Immunoglobulin E ( IgE ) -mediated irregular immune response against environmental triggers. In individuals with a sensitized immune system, allergen-specific IgE antibodies are produced in answer to environmental allergens.13-14 Worldwide, sensitization ( IgE antibodies ) to allergies in the environment is present in up to 40 percentage of the population.15 Certain outdoor and indoor antigens such as pollen, model, animal dander and theater dust mites contain protease enzymes. When they are inhaled and come into lead contact with the nasal pit endothelium, these protease enzymes can injure tissues and induce a transient IgE-mediated allergic inflammatory response.16 In-vitro test has shown that protein fractions contained in the flinch egg, including ovomucoids and ovoinhibitors, act as serine protease inhibitors.17-18 By inhibiting proteases, AllerGuard Express bioactives help reduce the symptoms of an allergic reaction .
Conclusion
There is no single magic trick pharmaceutical or nutraceutical that will eliminate allergies. however, given the solid and extensive human clinical research on quail egg powder ( commercially known as AllerGuard Express ), a well as its excellent condom visibility, the use of this nutraceutical offers promising results in helping to relieve allergic symptoms. VR
References:
1 Pawankar R, Canonica GW, Holgate ST, Lockey RF. WAO White Book on Allergy. Milwaukee, WI : World Allergy Organization ; 2011.
2 Schiller JS, Lucas JW, Ward BW, Peregoy JA. Summary health statistics for U.S. adults : National Health Interview Survey, 2010. National Center for Health Statistics. Vital Health Stat. 2012 ; 10 ( 252 ) :208 pgs. 3 american College of Allergy, Asthma, and Immunology. Asthma Facts. Retrieved January 22, 2016 from www.aaaai.org/about-the-aaaai/newsroom/asthma-statistics.aspx. 4 Federal Interagency Forum on Child and Family Statistics. America ’ s Children in brief : key National Indicators of Well-Being, 2012. Washington, DC : U.S. Government Printing Office. Retrieved January 22, 2016 from www.childstats.gov/pdf/ac2012/ ac_12.pdf. 5 american College of Allergy, Asthma, and Immunology. Allergy Facts. Retrieved January 22, 2016 from hypertext transfer protocol : //acaai.org/news/facts-statistics/allergies. 6 Allergy Treatment : Allergy Medication. American College of Allergy, Asthma & Immunology. 2014. Retrieved January 22, 2016 from hypertext transfer protocol : //acaai.org/allergies/treatment/medication. 7 Truffier JC. Approche therapeutique de la maladie allergique par consumption five hundred ’ oeufs de caille. La Clinique. 1978 ; 22 : 2-4. 8 Bruttman G. Study 1 ( réf. 82-83-1 ) : debris Mite-Induced Allergic Asthma In Children. & Bruttman G. “ Ovix ” Quail Egg Homogenate : A clinical evaluation. La Medicina Biologica. April-June 1995 ; 2:25-29. 9 Bruttman G. Study 2 ( réf. 83-2 ) : exclusive Pollen-Induced Rhinitis. & Bruttman G. “ Ovix ” Quail Egg Homogenate : A clinical evaluation. La Medicina Biologica. April-June 1995 ; 2:25-29. 10 Bruttman G. Study 3 ( réf. 83-3 ) : Pollen-Induced Rhinitis. & Bruttman G. “ Ovix ” Quail Egg Homogenate : A clinical evaluation. La Medicina Biologica. April-June 1995 ; 2:25-29. 11 Bruttman G. Study 4 ( réf. 88-1 ) : Pollen-Induced Allergic Rhinitis. & Bruttman G. “ Ovix ” Quail Egg Homogenate : A clinical evaluation. La Medicina Biologica. April-June 1995 ; 2:25-29. 12 Benichou AC, Armanet M, Bussiere A, Chevreau N, Cardot J-M, Tetard J. A Proprietary Blend of Quail Egg for the Attenuation of Nasal Provocation with a Standardized Allergenic Challenge : A randomize, double-blind, placebo-controlled cogitation. Food Sci Nutr. 2014 Nov ; 2 ( 6 ) :655-63. 13 Bousquet J, Khaltaev N, Cruz AA, Denburg J, Fokkens WJ, Togias A, et aluminum. Allergic Rhinitis and its impact on Asthma ( ARIA ) 2008 update ( in collaboration with the World Health Organization, GA ( 2 ) LEN and AllerGen ). Allergy. 2008 ; 63 Suppl 86:8-160. 14 Reed CE, Kita H. The role of protease activation of ignition in allergic respiratory diseases. J Allergy Clin Immunol. 2004 Nov ; 114 ( 5 ) :997-1008. 15 Pawankar R, Canonica GW, Holgate ST, Lockey RF. WAO White Book on Allergy. Milwaukee, WI : World Allergy Organization ; 2011. 16 Widmer F, Hayes PJ, Whittaker RG, Kumar RK. Substrate predilection profiles of proteases released by allergenic pollens. Clin Exp Allergy. 2000 Apr ; 30 ( 4 ) :571-6.
17 Feeney RE, Means GE, Bigler JC. prohibition of human trypsin, plasmin, and thrombin by naturally occurring inhibitors of proteolytic enzymes. J Biol Chem. 1969 ; 244 ( 8 ) :1957-1960. 18 Takahashi K, Kitao S, Tashiro M, Asao T, Kanamori M. Inhibitory specificity against diverse trypsins and stability of ovomucoid from japanese quail egg white. J Nutr Sci Vitaminol ( Tokyo ). december 1994 ; 40 ( 6 ) :593-601. Gene Bruno, MS, MHS, the dean of academics for Huntington College of Health Sciences, is a dietician, herbalist, writer and educator. For more than 30 years he has educated and trail natural product retailers and health caution professionals, has researched and formulated natural products for dozens of dietary accessory companies, and has written articles on nutrition, herb tea music, nutraceuticals and consolidative health issues for trade wind, consumer magazines and peer-reviewed publications. He can be reached at gbruno @ hchs.edu .
